In vivo 11C-PBR-28 PET
Microglial Mitochondria
Neurobiology of Aging & Disease Laboratory
The Barron Lab Website
Welcome to the Barron LabLee Kong Chian School of Medicine, Nanyang Technological University, Singapore
Research Themes:
Inflammation & Alzheimer's disease
Aging is tightly associated with chronic inflammation, which has been identified as both a key contributor to the initiation and progression of Alzheimer`s disease and a compelling therapeutic target.
Neurosteroidogenesis & neuropsychiatric disease
Neuroactive steroid hormones are potent endogenous neuromodulators affecting complex behaviors including anxiety and depression, altering susceptibility to neuropsychiatric disease and have been implicated in cognitive aging.
Lifestyle factors for successful aging
Obesity, metabolic syndrome and diabetes are leading global health issues with growing evidence that metabolic abnormalities at midlife may increase the risk of cognitive decline and Alzheimer`s disease in later life.